Differential Coupling of Adult-Born Granule Cells to Parvalbumin and Somatostatin Interneurons

Summary: A strong GABAergic tone imposes sparse levels of activity in the dentate gyrus of the hippocampus. This balance is challenged by the addition of new granule cells (GCs) with high excitability. How developing GCs integrate within local inhibitory networks remains unknown. We used optogenetic...

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Bibliographic Details
Main Authors: Ayelén I. Groisman, Sung M. Yang, Alejandro F. Schinder
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719316444