Quantification of heterogeneity in human CD8+ T cell responses to vaccine antigens: an HLA-guided perspective

Quantification of heterogeneity in human CD8+ T cell responses to vaccine antigens: an HLA-guided perspective

Vaccines have historically played a pivotal role in controlling epidemics. Effective vaccines for viruses causing significant human disease, e.g., Ebola, Lassa fever, or Crimean Congo hemorrhagic fever virus, would be invaluable to public health strategies and counter-measure development missions. H...

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Bibliographic Details
Main Authors: Duane C. Harris, Apoorv Shanker, Makaela M. Montoya, Trent R. Llewellyn, Anna R. Matuszak, Aditi Lohar, Jessica Z. Kubicek-Sutherland, Ying Wai Li, Kristen Wilding, Ben Mcmahon, Sandrasegaram Gnanakaran, Ruy M. Ribeiro, Alan S. Perelson, Carmen Molina-París
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Immunology
Subjects:
HLA class I
vaccine
epitope
CD8 + T cell
immune response
correlate of protection
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1420284/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1420284/full

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