Haploidentical hematopoietic stem cell transplantation as individual treatment option in pediatric patients with very high-risk sarcomas

BackgroundPrognosis of children with primary disseminated or metastatic relapsed sarcomas remains dismal despite intensification of conventional therapies including high-dose chemotherapy. Since haploidentical hematopoietic stem cell transplantation (haplo-HSCT) is effective in the treatment of hema...

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Main Authors: Thomas Eichholz, Michaela Döring, Stefano Giardino, Bernd Gruhn, Christian Seitz, Tim Flaadt, Wolfgang Schwinger, Martin Ebinger, Ursula Holzer, Markus Mezger, Heiko-Manuel Teltschik, Monika Sparber-Sauer, Ewa Koscielniak, Michael Abele, Rupert Handgretinger, Peter Lang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1064190/full