A Systematic Review and Critical Assessment of Breast Cancer Risk Prediction Tools Incorporating a Polygenic Risk Score for the General Population

A Systematic Review and Critical Assessment of Breast Cancer Risk Prediction Tools Incorporating a Polygenic Risk Score for the General Population

Single nucleotide polymorphisms (SNPs) in the form of a polygenic risk score (PRS) have emerged as a promising factor that could improve the predictive performance of breast cancer (BC) risk prediction tools. This study aims to appraise and critically assess the current evidence on these tools. Stud...

Full description

Bibliographic Details
Main Authors: Cynthia Mbuya-Bienge, Nora Pashayan, Cornelia D. Kazemali, Julie Lapointe, Jacques Simard, Hermann Nabi
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Cancers
Subjects:
breast cancer
polygenic risk score (PRS)
risk prediction tools
non-genetic risk factors
systematic review
Online Access:https://www.mdpi.com/2072-6694/15/22/5380

Internet

https://www.mdpi.com/2072-6694/15/22/5380

Similar Items