Cerebro-cerebellar functional neuroplasticity mediates the effect of electric field on electroconvulsive therapy outcomes

Abstract Electroconvulsive therapy (ECT) is the most effective treatment for severe depression and works by applying an electric current through the brain. The applied current generates an electric field (E-field) and seizure activity, changing the brain’s functional organization. The E-field, which...

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Bibliographic Details
Main Authors: Zening Fu, Christopher C. Abbott, Jeremy Miller, Zhi-De Deng, Shawn M. McClintock, Mohammad S. E. Sendi, Jing Sui, Vince D. Calhoun
Format: Article
Language:English
Published: Nature Publishing Group 2023-02-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-023-02312-w