Fatal Lassa fever in cynomolgus monkeys is associated with systemic viral dissemination and inflammation.

Fatal Lassa fever in cynomolgus monkeys is associated with systemic viral dissemination and inflammation.

The pathogenesis of Lassa fever has not yet been fully deciphered, particularly as concerns the mechanisms determining whether acute infection is controlled or leads to catastrophic illness and death. Using a cynomolgus monkey model of Lassa virus (LASV) infection reproducing the different outcomes...

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Bibliographic Details
Main Authors: Jimmy Hortion, Emeline Perthame, Blaise Lafoux, Laura Soyer, Stéphanie Reynard, Alexandra Journeaux, Clara Germain, Hélène Lopez-Maestre, Natalia Pietrosemoli, Nicolas Baillet, Séverine Croze, Catherine Rey, Catherine Legras-Lachuer, Sylvain Baize
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-12-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1012768

Internet

https://doi.org/10.1371/journal.ppat.1012768

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