Immune checkpoint inhibitors break whose heart? Perspectives from cardio-immuno-oncology

Immune checkpoint inhibitors break whose heart? Perspectives from cardio-immuno-oncology

Immune checkpoint inhibitors (ICIs) are monoclonal antibody antagonists, which can block cytotoxic T lymphocyte antigen-4 (CTLA-4), programmed death-1/ligand-1 (PD-1/PD-L1) pathways, and other molecules exploited by tumor cells to evade T cell-mediated immune response. ICIs have transformed the trea...

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Bibliographic Details
Main Authors: Yingying He, Hui Yu, Shuang Dai, Miao He, Ling Ma, Zihan Xu, Feng Luo, Li Wang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-03-01
Series:Genes and Diseases
Subjects:
Cancer management
Cardio-immuno-oncology multidisciplinary
Cardiotoxicity
Immune checkpoint inhibitors
Immune tolerance
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304223000478

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http://www.sciencedirect.com/science/article/pii/S2352304223000478

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