Failure of neutrophil migration toward infectious focus in severe sepsis: a critical event for the outcome of this syndrome

Failure of neutrophil migration toward infectious focus in severe sepsis: a critical event for the outcome of this syndrome

Sepsis is a systemic inflammatory response commonly caused by bacterial infection. We demonstrated that the outcome of sepsis induced by cecal ligation and puncture (CLP) correlates with the severity of the neutrophil migration failure towards infectious focus. Failure appears to be due to a decreas...

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Bibliographic Details
Main Authors: José Carlos Alves-Filho, Claudia Benjamim, Beatriz Martins Tavares-Murta, Fernando Q Cunha
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2005-03-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
sepsis
neutrophil migration
nitric oxide
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000900038

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000900038

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