Enhancing Metal-binding with Noncanonical Coordinating Amino Acids

More than 50% of proteinogenic amino acid sidechains can bind metal ions, enabling proteins and peptides to bear these ions as cofactors. Nevertheless, post-translational modifications and incorporation of noncanonical amino acids bestow peptides and proteins myriads of other coordination capabiliti...

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Bibliographic Details
Main Authors: Luca Sauser, Michal S. Shoshan
Format: Article
Language:deu
Published: Swiss Chemical Society 2021-06-01
Series:CHIMIA
Subjects:
Online Access:https://www.ingentaconnect.com/contentone/scs/chimia/2021/00000075/00000006/art00014