IL-11 system participates in pulmonary artery remodeling and hypertension in pulmonary fibrosis

Abstract Background Pulmonary hypertension (PH) associated to idiopathic pulmonary fibrosis (IPF) portends a poor prognosis. IL-11 has been implicated in fibrotic diseases, but their role on pulmonary vessels is unknown. Here we analyzed the contribution of IL-11 to PH in patients with IPF and the p...

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Bibliographic Details
Main Authors: Javier Milara, Inés Roger, Paula Montero, Enrique Artigues, Juan Escrivá, Julio Cortijo
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Respiratory Research
Subjects:
Online Access:https://doi.org/10.1186/s12931-022-02241-0