Therapeutic dendritic cell cancer vaccines in hematologic malignancies

Abstract Tumor cells present antigen in the context of negative costimulation and immunosuppressive factors, resulting in the inhibition of T cell activation and immune tolerance. Dendritic cells (DCs) are a complex network of antigen presenting cells that play a critical role in maintaining the equ...

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Bibliographic Details
Main Authors: Poorva Bindal, Jacalyn Rosenblatt, David Avigan
Format: Article
Language:English
Published: Wiley 2021-06-01
Series:ImmunoMedicine
Subjects:
Online Access:https://doi.org/10.1002/imed.1022