Hydrogen Peroxide Induces α-Tubulin Detyrosination and Acetylation and Impacts Breast Cancer Metastatic Phenotypes

Hydrogen Peroxide Induces α-Tubulin Detyrosination and Acetylation and Impacts Breast Cancer Metastatic Phenotypes

Levels of hydrogen peroxide are highly elevated in the breast tumor microenvironment compared to normal tissue. Production of hydrogen peroxide is implicated in the mechanism of action of many anticancer therapies. Several lines of evidence suggest hydrogen peroxide mediates breast carcinogenesis an...

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Bibliographic Details
Main Authors: Megan B. Stemberger, Julia A. Ju, Keyata N. Thompson, Trevor J. Mathias, Alexandra E. Jerrett, Katarina T. Chang, Eleanor C. Ory, David A. Annis, Makenzy L. Mull, Darin E. Gilchrist, Michele I. Vitolo, Stuart S. Martin
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Cells
Subjects:
tumor microenvironment
reactive oxygen species
microtubules
microtentacles
Online Access:https://www.mdpi.com/2073-4409/12/9/1266

Internet

https://www.mdpi.com/2073-4409/12/9/1266

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