Generation of a Novel Nkx6-1 Venus Fusion Reporter Mouse Line

Generation of a Novel Nkx6-1 Venus Fusion Reporter Mouse Line

Nkx6-1 is a member of the Nkx family of homeodomain transcription factors (TFs) that regulates motor neuron development, neuron specification and pancreatic endocrine and β-cell differentiation. To facilitate the isolation and tracking of Nkx6-1-expressing cells, we have generated a novel Nkx6-1 Ven...

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Bibliographic Details
Main Authors: Ingo Burtscher, Marta Tarquis-Medina, Ciro Salinno, Silvia Schirge, Julia Beckenbauer, Mostafa Bakhti, Heiko Lickert
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
Nkx6-1
pancreas development
fluorescent reporter
endocrine lineage
secondary transition
β-cells
Online Access:https://www.mdpi.com/1422-0067/22/7/3434

Internet

https://www.mdpi.com/1422-0067/22/7/3434

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