Crosstalk between the CBM complex/NF-κB and MAPK/P27 signaling pathways of regulatory T cells contributes to the tumor microenvironment

Crosstalk between the CBM complex/NF-κB and MAPK/P27 signaling pathways of regulatory T cells contributes to the tumor microenvironment

Regulatory T cells (Tregs), which execute their immunosuppressive functions by multiple mechanisms, have been verified to contribute to the tumor microenvironment (TME). Numerous studies have shown that the activation of the CBM complex/NF-κB signaling pathway results in the expression of hypoxia-in...

Full description

Bibliographic Details
Main Authors: Tongbing Qi, Ying Luo, Weitong Cui, Yue Zhou, Xuan Ma, Dongming Wang, Xuewen Tian, Qinglu Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
regulatory T cells
tumor microenvironment
CBM signaling pathway
MAPK/P27 signaling pathway
CARMA1
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.911811/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.911811/full

Similar Items