No major change in vCJD agent strain after secondary transmission via blood transfusion.

BACKGROUND:The identification of transmission of variant Creutzfeldt-Jakob disease (vCJD) by blood transfusion has prompted investigation to establish whether there has been any alteration in the vCJD agent following this route of secondary transmission. Any increase in virulence or host adaptation...

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Bibliographic Details
Main Authors: Matthew T Bishop, Diane L Ritchie, Robert G Will, James W Ironside, Mark W Head, Val Thomson, Moira Bruce, Jean C Manson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2478718?pdf=render