Neuropharmacological Evidence Implicating Drug-Induced Glutamate Receptor Dysfunction in Affective and Cognitive Sequelae of Subchronic Methamphetamine Self-Administration in Mice

Neuropharmacological Evidence Implicating Drug-Induced Glutamate Receptor Dysfunction in Affective and Cognitive Sequelae of Subchronic Methamphetamine Self-Administration in Mice

Methamphetamine (MA) is a highly addictive drug, and MA use disorder is often comorbid with anxiety and cognitive impairment. These comorbid conditions are theorized to reflect glutamate-related neurotoxicity within the frontal cortical regions. However, our prior studies of MA-sensitized mice indic...

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Bibliographic Details
Main Authors: Christopher J. E. Denning, Lauren E. Madory, Jessica N. Herbert, Ryan A. Cabrera, Karen K. Szumlinski
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
NMDA receptor
Group 1 mGluR
anxiety
sex differences
spatial learning
working memory
Online Access:https://www.mdpi.com/1422-0067/25/3/1928

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https://www.mdpi.com/1422-0067/25/3/1928

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