Fibroblast Growth Factor Receptor 2 Isoforms Detected via Novel RNA ISH as Predictive Biomarkers for Progestin Therapy in Atypical Hyperplasia and Low-Grade Endometrial Cancer

Fibroblast Growth Factor Receptor 2 Isoforms Detected via Novel RNA ISH as Predictive Biomarkers for Progestin Therapy in Atypical Hyperplasia and Low-Grade Endometrial Cancer

Women with atypical hyperplasia (AH) or well-differentiated early-stage endometrioid endometrial carcinoma (EEC) who wish to retain fertility and/or with comorbidities precluding surgery, are treated with progestin. Clinically approved predictive biomarkers for progestin therapy remain an unmet need...

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Bibliographic Details
Main Authors: Asmerom T. Sengal, Deborah Smith, Rebecca Rogers, Cameron E. Snell, Elizabeth D. Williams, Pamela M. Pollock
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
atypical hyperplasia
endometrioid endometrial cancer
biomarkers
FGFR2b
FGFR2c
LNG-IUD/Mirena
Online Access:https://www.mdpi.com/2072-6694/13/7/1703

Internet

https://www.mdpi.com/2072-6694/13/7/1703

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