Discovery of directional and nondirectional pioneer transcription factors by modeling DNase profile magnitude and shape
We describe protein interaction quantitation (PIQ), a computational method for modeling the magnitude and shape of genome-wide DNase I hypersensitivity profiles to identify transcription factor (TF) binding sites. Through the use of machine-learning techniques, PIQ identified binding sites for >7...
| Main Authors: | , , , , , , , , |
|---|---|
| 其他作者: | |
| 格式: | 文件 |
| 语言: | en_US |
| 出版: |
Nature Publishing Group
2015
|
| 在线阅读: | http://hdl.handle.net/1721.1/100228 https://orcid.org/0000-0003-0521-5855 https://orcid.org/0000-0002-2199-0379 https://orcid.org/0000-0003-1709-4034 |