The AlkB Family of Fe(II)/α-Ketoglutarate-dependent Dioxygenases: Repairing Nucleic Acid Alkylation Damage and Beyond

The AlkB Family of Fe(II)/α-Ketoglutarate-dependent Dioxygenases: Repairing Nucleic Acid Alkylation Damage and Beyond

The AlkB family of Fe(II)- and α-ketoglutarate-dependent dioxygenases is a class of ubiquitous direct reversal DNA repair enzymes that remove alkyl adducts from nucleobases by oxidative dealkylation. The prototypical and homonymous family member is an Escherichia coli “adaptive response” protein tha...

书目详细资料
Main Authors:	Fedeles, Bogdan I., Singh, Vipender, Delaney, James C., Li, Deyu, Essigmann, John M.
其他作者:	Massachusetts Institute of Technology. Center for Environmental Health Sciences
格式:	文件
语言:	en_US
出版:	American Society for Biochemistry and Molecular Biology (ASBMB) 2015
在线阅读:	http://hdl.handle.net/1721.1/100429 https://orcid.org/0000-0001-6159-0778 https://orcid.org/0000-0002-8241-4834 https://orcid.org/0000-0002-2196-5691

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