HaploReg v4: systematic mining of putative causal variants, cell types, regulators and target genes for human complex traits and disease

More than 90% of common variants associated with complex traits do not affect proteins directly, but instead the circuits that control gene expression. This has increased the urgency of understanding the regulatory genome as a key component for translating genetic results into mechanistic insights a...

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Bibliographic Details
Main Authors: Ward, Lucas D., Kellis, Manolis
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:en_US
Published: Oxford University Press 2016
Online Access:http://hdl.handle.net/1721.1/100576
https://orcid.org/0000-0002-8017-809X