Algorithmic co-optimization of genetic constructs and growth conditions: application to 6-ACA, a potential nylon-6 precursor
Optimizing bio-production involves strain and process improvements performed as discrete steps. However, environment impacts genotype and a strain that is optimal under one set of conditions may not be under different conditions. We present a methodology to simultaneously vary genetic and process fa...
Main Authors: | Zhou, Hui, Vonk, Brenda, Roubos, Johannes A., Voigt, Christopher A., Bovenberg, Roel A. L. |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Language: | en_US |
Published: |
Oxford University Press
2016
|
Online Access: | http://hdl.handle.net/1721.1/100578 https://orcid.org/0000-0003-0844-4776 |
Similar Items
-
Genetic Circuit Performance under Conditions Relevant for Industrial Bioreactors
by: Moser, Felix, et al.
Published: (2014) -
Nylon 6,6/POSS Nanocomposites
by: Lim, Yi Yu.
Published: (2009) -
Trade-offs between tRNA abundance and mRNA secondary structure support smoothing of translation elongation rate
by: Roubos, J. A., et al.
Published: (2015) -
Mechanical properties of PDMS-nylon-6 diblock copolymer and its blends with homo nylon-6
by: Mukai, Uchu
Published: (2005) -
Thermal degradation of nylon 6 nanocomposites
by: Wee, Sabrina Gui Fen.
Published: (2009)