Multiple stiffening effects of nanoscale knobs on human red blood cells infected with Plasmodium falciparum malaria parasite

During its asexual development within the red blood cell (RBC), Plasmodium falciparum (Pf), the most virulent human malaria parasite, exports proteins that modify the host RBC membrane. The attendant increase in cell stiffness and cytoadherence leads to sequestration of infected RBCs in microvascula...

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Bibliographic Details
Main Authors: Zhang, Yao, Huang, Changjin, Kim, Sangtae, Golkaram, Mahdi, Dixon, Matthew W. A., Tilley, Leann, Li, Ju, Zhang, Sulin, Suresh, Subra
Other Authors: Massachusetts Institute of Technology. Department of Materials Science and Engineering
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2016
Online Access:http://hdl.handle.net/1721.1/100588
https://orcid.org/0000-0002-7959-8249
https://orcid.org/0000-0002-7841-8058