Calibrating the Human Mutation Rate via Ancestral Recombination Density in Diploid Genomes

The human mutation rate is an essential parameter for studying the evolution of our species, interpreting present-day genetic variation, and understanding the incidence of genetic disease. Nevertheless, our current estimates of the rate are uncertain. Most notably, recent approaches based on countin...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Lipson, Mark, Loh, Po-Ru, Sankararaman, Sriram, Patterson, Nick, Berger, Bonnie, Reich, David
Weitere Verfasser: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Artikel
Sprache:en_US
Veröffentlicht: Public Library of Science 2016
Online Zugang:http://hdl.handle.net/1721.1/100589
https://orcid.org/0000-0002-2724-7228