Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer’s disease

Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer’s disease

Alzheimer’s disease (AD) is a severe age-related neurodegenerative disorder characterized by accumulation of amyloid-β plaques and neurofibrillary tangles, synaptic and neuronal loss, and cognitive decline. Several genes have been implicated in AD, but chromatin state alterations during neurodegener...

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Bibliographic Details
Main Authors: Gjoneska, Elizabeta, Pfenning, Andreas R., Mathys, Hansruedi, Quon, Gerald, Kundaje, Anshul, Tsai, Li-Huei, Kellis, Manolis
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:en_US
Published: American Association for the Advancement of Science (AAAS) 2016
Online Access:http://hdl.handle.net/1721.1/100729
https://orcid.org/0000-0002-3447-9801
https://orcid.org/0000-0003-1262-0592
https://orcid.org/0000-0002-1716-0153
https://orcid.org/0000-0002-3255-4740
https://orcid.org/0000-0001-5842-5245

Internet

http://hdl.handle.net/1721.1/100729
https://orcid.org/0000-0002-3447-9801
https://orcid.org/0000-0003-1262-0592
https://orcid.org/0000-0002-1716-0153
https://orcid.org/0000-0002-3255-4740
https://orcid.org/0000-0001-5842-5245

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