PTP1B-dependent regulation of receptor tyrosine kinase signaling by the actin-binding protein Mena

PTP1B-dependent regulation of receptor tyrosine kinase signaling by the actin-binding protein Mena

During breast cancer progression, alternative mRNA splicing produces functionally distinct isoforms of Mena, an actin regulator with roles in cell migration and metastasis. Aggressive tumor cell subpopulations express Mena[superscript INV], which promotes tumor cell invasion by potentiating EGF resp...

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Bibliographic Details
Main Authors: Hughes, Shannon Kay, Oudin, Madeleine Julie, Tadros, Jenny, Neil, Jason Robert, Del Rosario, Amanda M., Joughin, Brian A., Ritsma, Laila, Wyckoff, Jeff, Vasile, Eliza, Eddy, Robert, Philippar, Ulrike, Lussiez, Alisha, Condeelis, John S., van Rheenen, Jacco, White, Forest M., Lauffenburger, Douglas A., Gertler, Frank
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: American Society for Cell Biology 2016
Online Access:http://hdl.handle.net/1721.1/100747
https://orcid.org/0000-0002-1545-1651
https://orcid.org/0000-0001-6988-4260
https://orcid.org/0000-0003-3214-4554

Internet

http://hdl.handle.net/1721.1/100747
https://orcid.org/0000-0002-1545-1651
https://orcid.org/0000-0001-6988-4260
https://orcid.org/0000-0003-3214-4554

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