Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers

Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers

Genetic studies of type 1 diabetes (T1D) have identified 50 susceptibility regions, finding major pathways contributing to risk, with some loci shared across immune disorders. To make genetic comparisons across autoimmune disorders as informative as possible, a dense genotyping array, the Immunochip...

Full description

Bibliographic Details
Main Authors: Onengut-Gumuscu, Suna, Chen, Wei-Min, Burren, Oliver, Farber, Emily, Szpak, Michal, Schofield, Ellen, Achuthan, Premanand, Guo, Hui, Stevens, Helen, Kundaje, Anshul, Kellis, Manolis, Deloukas, Panos, Wallace, Chris, Concannon, Patrick, Cooper, Nick J., Quinlan, Aaron R., Mychaleckyj, Josyf C., Bonnie, Jessica K., Fortune, Mary D., Walker, Neil M., Ward, Lucas D., Daly, Mark J., Barrett, Jeffrey C., Cooper, Jason D., Todd, John A., Rich, Stephen S.
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:en_US
Published: Nature Publishing Group 2016
Online Access:http://hdl.handle.net/1721.1/100781
https://orcid.org/0000-0002-8017-809X

Internet

http://hdl.handle.net/1721.1/100781
https://orcid.org/0000-0002-8017-809X

Similar Items