Spatiotemporal expression and transcriptional perturbations by long noncoding RNAs in the mouse brain

Long noncoding RNAs (lncRNAs) have been implicated in numerous cellular processes including brain development. However, the in vivo expression dynamics and molecular pathways regulated by these loci are not well understood. Here, we leveraged a cohort of 13 lncRNA-null mutant mouse models to investi...

Full description

Bibliographic Details
Main Authors: Goff, Loyal A., Groff, Abigail F., Sauvageau, Martin, Trayes-Gibson, Zachary, Sanchez-Gomez, Diana B., Morse, Michael, Martin, Ryan D., Elcavage, Lara E., Liapis, Stephen C., Gonzalez-Celeiro, Meryem, Plana, Olivia, Li, Eric, Gerhardinger, Chiara, Tomassy, Giulio S., Arlotta, Paola, Rinn, John L.
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2016
Online Access:http://hdl.handle.net/1721.1/100788