Recombinase-based conditional and reversible gene regulation via XTR alleles

Synthetic biological tools that enable precise regulation of gene function within in vivo systems have enormous potential to discern gene function in diverse physiological settings. Here we report the development and characterization of a synthetic gene switch that, when targeted in the mouse germli...

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Bibliographic Details
Main Authors: Robles-Oteiza, Camila, Yates, Travis, Cicchini, Michelle, Lauderback, Brian, Burds, Aurora A., Winslow, Monte M., Feldser, David M., Taylor, Sarah E., Cashman, Chris, Jacks, Tyler E
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Language:en_US
Published: 2016
Online Access:http://hdl.handle.net/1721.1/100823
https://orcid.org/0000-0001-5785-8911