Identification of neurotoxic cytokines by profiling Alzheimer’s disease tissues and neuron culture viability screening

Identification of neurotoxic cytokines by profiling Alzheimer’s disease tissues and neuron culture viability screening

Alzheimer’s disease (AD) therapeutics based on the amyloid hypothesis have shown minimal efficacy in patients, suggesting that the activity of amyloid beta (Aβ) represents only one aspect of AD pathogenesis. Since neuroinflammation is thought to play an important role in AD, we hypothesized that cyt...

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Detalhes bibliográficos
Main Authors: Wood, Levi B., Winslow, Ashley R., Proctor, Elizabeth A., McGuone, Declan, Mordes, Daniel A., Frosch, Matthew P., Hyman, Bradley T., Lauffenburger, Douglas A., Haigis, Kevin M.
Outros Autores: Massachusetts Institute of Technology. Department of Biological Engineering
Formato: Artigo
Idioma:en_US
Publicado em: Nature Publishing Group 2016
Acesso em linha:http://hdl.handle.net/1721.1/100929
https://orcid.org/0000-0002-7627-2198

Internet

http://hdl.handle.net/1721.1/100929
https://orcid.org/0000-0002-7627-2198

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