In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight

In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight

Dysfunctional endothelium contributes to more diseases than any other tissue in the body. Small interfering RNAs (siRNAs) can help in the study and treatment of endothelial cells in vivo by durably silencing multiple genes simultaneously, but efficient siRNA delivery has so far remained challenging....

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Bibliographic Details
Main Authors: Dahlman, James E., Jhunjhunwala, Siddharth, Shaw, Taylor E., Xing, Yiping, Sahay, Gaurav, Bader, Andrew, Yin, Hao, Dong, Yizhou, Jiang, Shan, Seedorf, Danielle, Dave, Apeksha, Sandhu, Kamaljeet Singh, Webber, Matthew, Lytton-Jean, Abigail K. R., Levins, Christopher G., Anderson, Daniel Griffith, Khan, Omar Fizal, Bogorad, Roman, Ruda, Vera, Langer, Robert S
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:en_US
Published: Nature Publishing Group 2016
Online Access:http://hdl.handle.net/1721.1/101130
https://orcid.org/0000-0002-2100-1171
https://orcid.org/0000-0001-5786-0659
https://orcid.org/0000-0001-5629-4798
https://orcid.org/0000-0001-6898-3793
https://orcid.org/0000-0003-3811-2369
https://orcid.org/0000-0001-8223-035X
https://orcid.org/0000-0003-0624-3532
https://orcid.org/0000-0001-8046-2288
https://orcid.org/0000-0003-4255-0492

Internet

http://hdl.handle.net/1721.1/101130
https://orcid.org/0000-0002-2100-1171
https://orcid.org/0000-0001-5786-0659
https://orcid.org/0000-0001-5629-4798
https://orcid.org/0000-0001-6898-3793
https://orcid.org/0000-0003-3811-2369
https://orcid.org/0000-0001-8223-035X
https://orcid.org/0000-0003-0624-3532
https://orcid.org/0000-0001-8046-2288
https://orcid.org/0000-0003-4255-0492

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