Nanoparticle-formulated siRNA targeting integrins inhibits hepatocellular carcinoma progression in mice

Nanoparticle-formulated siRNA targeting integrins inhibits hepatocellular carcinoma progression in mice

Integrins play an important role during development, regulating cell differentiation, proliferation and survival. Here we show that knockdown of integrin subunits slows down the progression of hepatocellular carcinoma (HCC). Using nanoparticulate delivery of short interfering RNAs targeting β1 and α...

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Bibliographic Details
Main Authors: Yin, Hao, Zeigerer, Anja, Nonaka, Hidenori, Zerial, Marino, Koteliansky, Victor, Anderson, Daniel Griffith, Ruda, Vera, Bogorad, Roman
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:en_US
Published: Nature Publishing Group 2016
Online Access:http://hdl.handle.net/1721.1/101131
https://orcid.org/0000-0001-5629-4798
https://orcid.org/0000-0001-6898-3793

Internet

http://hdl.handle.net/1721.1/101131
https://orcid.org/0000-0001-5629-4798
https://orcid.org/0000-0001-6898-3793

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