CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling
CRISPR-Cas9 is a versatile genome editing technology for studying the functions of genetic elements. To broadly enable the application of Cas9 in vivo, we established a Cre-dependent Cas9 knockin mouse. We demonstrated in vivo as well as ex vivo genome editing using adeno-associated virus (AAV)-, le...
Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | en_US |
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Elsevier
2016
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Online Access: | http://hdl.handle.net/1721.1/101139 https://orcid.org/0000-0003-2782-2509 https://orcid.org/0000-0003-1465-1691 https://orcid.org/0000-0002-8021-277X https://orcid.org/0000-0001-5629-4798 https://orcid.org/0000-0001-8567-2049 https://orcid.org/0000-0001-6683-5498 https://orcid.org/0000-0001-8046-2288 https://orcid.org/0000-0003-4255-0492 |
Internet
http://hdl.handle.net/1721.1/101139https://orcid.org/0000-0003-2782-2509
https://orcid.org/0000-0003-1465-1691
https://orcid.org/0000-0002-8021-277X
https://orcid.org/0000-0001-5629-4798
https://orcid.org/0000-0001-8567-2049
https://orcid.org/0000-0001-6683-5498
https://orcid.org/0000-0001-8046-2288
https://orcid.org/0000-0003-4255-0492