CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling

CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling

CRISPR-Cas9 is a versatile genome editing technology for studying the functions of genetic elements. To broadly enable the application of Cas9 in vivo, we established a Cre-dependent Cas9 knockin mouse. We demonstrated in vivo as well as ex vivo genome editing using adeno-associated virus (AAV)-, le...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Chen, Sidi, Zhou, Yang, Yim, Michael J., Swiech, Lukasz, Kempton, Hannah R., Dahlman, James E., Parnas, Oren, Eisenhaure, Thomas M., Jovanovic, Marko, Graham, Daniel B., Jhunjhunwala, Siddharth, Heidenreich, Matthias, Xavier, Ramnik J., Hacohen, Nir, Regev, Aviv, Feng, Guoping, Sharp, Phillip A., Zhang, Feng, Anderson, Daniel Griffith, Kempton, Hannah R., Dahlman, James E., Langer, Robert S, Platt, Randall Jeffrey, Yim, Michael
अन्य लेखक: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
स्वरूप: लेख
भाषा:en_US
प्रकाशित: Elsevier 2016
ऑनलाइन पहुंच:http://hdl.handle.net/1721.1/101139
https://orcid.org/0000-0003-2782-2509
https://orcid.org/0000-0003-1465-1691
https://orcid.org/0000-0002-8021-277X
https://orcid.org/0000-0001-5629-4798
https://orcid.org/0000-0001-8567-2049
https://orcid.org/0000-0001-6683-5498
https://orcid.org/0000-0001-8046-2288
https://orcid.org/0000-0003-4255-0492

इंटरनेट

http://hdl.handle.net/1721.1/101139
https://orcid.org/0000-0003-2782-2509
https://orcid.org/0000-0003-1465-1691
https://orcid.org/0000-0002-8021-277X
https://orcid.org/0000-0001-5629-4798
https://orcid.org/0000-0001-8567-2049
https://orcid.org/0000-0001-6683-5498
https://orcid.org/0000-0001-8046-2288
https://orcid.org/0000-0003-4255-0492

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