A defined synthetic substrate for serum-free culture of human stem cell derived cardiomyocytes with improved functional maturity identified using combinatorial materials microarrays

Cardiomyocytes from human stem cells have applications in regenerative medicine and can provide models for heart disease and toxicity screening. Soluble components of the culture system such as growth factors within serum and insoluble components such as the substrate on which cells adhere to are im...

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Bibliographic Details
Main Authors: Celiz, Adam D., Rajamohan, Divya, Davies, Martyn C., Alexander, Morgan R., Denning, Chris, Patel, Asha, Anderson, Daniel Griffith, Langer, Robert S
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:en_US
Published: Elsevier 2016
Online Access:http://hdl.handle.net/1721.1/101143
https://orcid.org/0000-0001-5629-4798
https://orcid.org/0000-0002-7266-9251
https://orcid.org/0000-0003-4255-0492