Layer-by-Layer Nanoparticles for Systemic Codelivery of an Anticancer Drug and siRNA for Potential Triple-Negative Breast Cancer Treatment

A single nanoparticle platform has been developed through the modular and controlled layer-by-layer process to codeliver siRNA that knocks down a drug-resistance pathway in tumor cells and a chemotherapy drug to challenge a highly aggressive form of triple-negative breast cancer. Layer-by-layer film...

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Bibliographic Details
Main Authors: Deng, Zhou J., Morton, Stephen Winford, Ben-Akiva, Elana, Shopsowitz, Kevin, Hammond, Paula T, Dreaden, Erik
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2016
Online Access:http://hdl.handle.net/1721.1/101180
https://orcid.org/0000-0002-4954-8443
https://orcid.org/0000-0003-3988-0837