Enhanced activity and stability of organophosphorus hydrolase via interaction with an amphiphilic polymer

A simple approach to enhancing the activity and stability of organophosphorus hydrolase (OPH) is developed based on interactions between the hydrophobic poly(propylene oxide) (PPO) block of amphiphilic Pluronics and the enzyme. This strategy provides an efficient route to new formulations for decont...

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Bibliographic Details
Main Authors: Kim, Minkyu, Huang, Aaron, Kang, Jeon Woong, Suthiwangcharoen, Nisaraporn, Nagarajan, Ramanathan, Gkikas, Emmanouil, Olsen, Bradley D
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:en_US
Published: Royal Society of Chemistry 2016
Online Access:http://hdl.handle.net/1721.1/101212
https://orcid.org/0000-0002-7272-7140
https://orcid.org/0000-0002-9476-6351
https://orcid.org/0000-0001-8334-5140
https://orcid.org/0000-0002-7356-5489