Neutralizing antibodies against West Nile virus identified directly from human B cells by single-cell analysis and next generation sequencing

West Nile virus (WNV) infection is an emerging mosquito-borne disease that can lead to severe neurological illness and currently has no available treatment or vaccine. Using microengraving, an integrated single-cell analysis method, we analyzed a cohort of subjects infected with WNV – recently infec...

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Bibliographic Details
Main Authors: Tsioris, Konstantinos, Gupta, Namita T., Ogunniyi, Adebola Oluwakayode, Qian, Feng, Yao, Yi, Wang, Xiaomei, Stern, Joel N. H., Chari, Raj, Briggs, Adrian W., Clouser, Christopher R., Vigneault, Francois, Church, George M., Garcia, Melissa N., Murray, Kristy O., Montgomery, Ruth R., Kleinstein, Steven H., Love, J. Christopher, Zimnisky, Ross Martin
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:en_US
Published: Royal Society of Chemistry 2016
Online Access:http://hdl.handle.net/1721.1/101221
https://orcid.org/0000-0003-1387-8472
https://orcid.org/0000-0003-0921-3144