Imaging Primary Lung Cancers in Mice to Study Radiation Biology

Purpose To image a genetically engineered mouse model of non–small-cell lung cancer with micro–computed tomography (micro-CT) to measure tumor response to radiation therapy. Methods and Materials The Cre-loxP system was used to generate primary lung cancers in mice with mutation in K-ras alone or...

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Bibliographic Details
Main Authors: Kirsch, David G., Grimm, Jan, Guimaraes, Alexander R., Wojtkiewicz, Gregory R., Perez, Bradford A., Santiago, Philip M., Anthony, Nikolas K., Forbes, Thomas, Doppke, Karen, Weissleder, Ralph, Jacks, Tyler E
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Language:en_US
Published: Elsevier 2016
Online Access:http://hdl.handle.net/1721.1/101255
https://orcid.org/0000-0001-5785-8911