Nkx2-1 Represses a Latent Gastric Differentiation Program in Lung Adenocarcinoma

Tissue-specific differentiation programs become dysregulated during cancer evolution. The transcription factor Nkx2-1 is a master regulator of pulmonary differentiation that is downregulated in poorly differentiated lung adenocarcinoma. Here we use conditional murine genetics to determine how the id...

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书目详细资料
Main Authors: Snyder, Eric L., Watanabe, Hideo, Magendantz, Margaret, Hoersch, Sebastian, Chen, Tiffany A., Wang, Diana G., Whittaker, Charles A., Meyerson, Matthew L., Kimura, Shioko, Chen, Tiffany A., Wang, Diana G., Whittaker, Charles A., Crowley, Denise G., Jacks, Tyler E, Snyder, Eric
其他作者: Koch Institute for Integrative Cancer Research at MIT
格式: 文件
语言:en_US
出版: Elsevier 2016
在线阅读:http://hdl.handle.net/1721.1/101256
https://orcid.org/0000-0001-5785-8911