Nkx2-1 Represses a Latent Gastric Differentiation Program in Lung Adenocarcinoma

Nkx2-1 Represses a Latent Gastric Differentiation Program in Lung Adenocarcinoma

Tissue-specific differentiation programs become dysregulated during cancer evolution. The transcription factor Nkx2-1 is a master regulator of pulmonary differentiation that is downregulated in poorly differentiated lung adenocarcinoma. Here we use conditional murine genetics to determine how the id...

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Bibliographic Details
Main Authors: Snyder, Eric L., Watanabe, Hideo, Magendantz, Margaret, Hoersch, Sebastian, Chen, Tiffany A., Wang, Diana G., Whittaker, Charles A., Meyerson, Matthew L., Kimura, Shioko, Chen, Tiffany A., Wang, Diana G., Whittaker, Charles A., Crowley, Denise G., Jacks, Tyler E, Snyder, Eric
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Language:en_US
Published: Elsevier 2016
Online Access:http://hdl.handle.net/1721.1/101256
https://orcid.org/0000-0001-5785-8911

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http://hdl.handle.net/1721.1/101256
https://orcid.org/0000-0001-5785-8911

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