Structure-Based Redesign of the Binding Specificity of Anti-Apoptotic Bcl-x[subscript L]
Many native proteins are multi-specific and interact with numerous partners, which can confound analysis of their functions. Protein design provides a potential route to generating synthetic variants of native proteins with more selective binding profiles. Redesigned proteins could be used as resear...
| Main Authors: | , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Elsevier
2016
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| Online Access: | http://hdl.handle.net/1721.1/101270 https://orcid.org/0000-0003-4074-8980 |