Differential regulation of evoked and spontaneous neurotransmitter release by C-terminal modifications of complexin

Complexins are small α-helical proteins that modulate neurotransmitter release by binding to SNARE complexes during synaptic vesicle exocytosis. They have been found to function as fusion clamps to inhibit spontaneous synaptic vesicle fusion in the absence of Ca[superscript 2+], while also promoting...

Full description

Bibliographic Details
Main Authors: Akbergenova, Yulia, Huntwork-Rodriguez, Sarah, Volfson, Dina, Littleton, J. Troy, Buhl, Lauren Kaye, Jorquera, Ramon
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2016
Online Access:http://hdl.handle.net/1721.1/101273
https://orcid.org/0000-0001-5576-2887