Efficacy of Sunitinib and Radiotherapy in Genetically Engineered Mouse Model of Soft-Tissue Sarcoma

Purpose Sunitinib (SU) is a multitargeted receptor tyrosine kinase inhibitor of the vascular endothelial growth factor and platelet-derived growth factor receptors. The present study examined SU and radiotherapy (RT) in a genetically engineered mouse model of soft tissue sarcoma (STS). Methods and...

Full description

Bibliographic Details
Main Authors: Yoon, Sam S., Stangenberg, Lars, Lee, Yoon-Jin, Rothrock, Courtney, Dreyfuss, Jonathan M., Baek, Kwan-Hyuck, Waterman, Peter R., Nielsen, G. Petur, Weissleder, Ralph, Mahmood, Umar, Park, Peter J., Dodd, Rebecca D., Fisher, Carolyn J., Ryeom, Sandra, Kirsch, David G., Jacks, Tyler E
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2016
Online Access:http://hdl.handle.net/1721.1/101278
https://orcid.org/0000-0001-5785-8911