Practical Theoretic Guidance for the Design of Tumor-Targeting Agents
Theoretical analyses of targeting agent pharmacokinetics provides specific guidance with respect to desirable design objectives such as agent size, affinity, and target antigen. These analyses suggest that IgG-sized macromolecular constructs exhibit the most favorable balance between systemic cleara...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Elsevier
2016
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| Online Access: | http://hdl.handle.net/1721.1/101376 https://orcid.org/0000-0003-2398-5896 https://orcid.org/0000-0001-7570-2080 |