Principles of Long Noncoding RNA Evolution Derived from Direct Comparison of Transcriptomes in 17 Species

The inability to predict long noncoding RNAs from genomic sequence has impeded the use of comparative genomics for studying their biology. Here, we develop methods that use RNA sequencing (RNA-seq) data to annotate the transcriptomes of 16 vertebrates and the echinoid sea urchin, uncovering thousand...

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Bibliographic Details
Main Authors: Hezroni, Hadas, Koppstein, David, Schwartz, Matthew G., Avrutin, Alexandra, Ulitsky, Igor, Bartel, David
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2016
Online Access:http://hdl.handle.net/1721.1/101429
https://orcid.org/0000-0002-3872-2856