Structure–mechanics relationships of collagen fibrils in the osteogenesis imperfecta mouse model
The collagen molecule, which is the building block of collagen fibrils, is a triple helix of two α1(I) chains and one α2(I) chain. However, in the severe mouse model of osteogenesis imperfecta (OIM), deletion of the COL1A2 gene results in the substitution of the α2(I) chain by one α1(I) chain. As th...
| Main Authors: | , , , , , , , |
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| 其他作者: | |
| 格式: | 文件 |
| 语言: | en_US |
| 出版: |
Royal Society
2016
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| 在线阅读: | http://hdl.handle.net/1721.1/101599 https://orcid.org/0000-0002-4173-9659 |