Improved Ribosome-Footprint and mRNA Measurements Provide Insights into Dynamics and Regulation of Yeast Translation

Ribosome-footprint profiling provides genome-wide snapshots of translation, but technical challenges can confound its analysis. Here, we use improved methods to obtain ribosome-footprint profiles and mRNA abundances that more faithfully reflect gene expression in Saccharomyces cerevisiae. Our result...

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Bibliographic Details
Main Authors: Weinberg, David E., Shah, Premal, Hussmann, Jeffrey A., Plotkin, Joshua B., Eichhorn, Stephen William, Bartel, David
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2016
Online Access:http://hdl.handle.net/1721.1/101696
https://orcid.org/0000-0002-6410-4699
https://orcid.org/0000-0002-3872-2856