A Small-Molecule Screen for Enhanced Homing of Systemically Infused Cells

A Small-Molecule Screen for Enhanced Homing of Systemically Infused Cells

Poor homing of systemically infused cells to disease sites may limit the success of exogenous cell-based therapy. In this study, we screened 9,000 signal-transduction modulators to identify hits that increase mesenchymal stromal cell (MSC) surface expression of homing ligands that bind to intercellu...

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Bibliographic Details
Main Authors: Levy, Oren, Mortensen, Luke J., Boquet, Gerald, Tong, Zhixiang, Perrault, Christelle, Benhamou, Brigitte, Zhang, Jidong, Stratton, Tara, Han, Edward, Safaee, Helia, Musabeyezu, Juliet, Yang, Zijiang, Multon, Marie-Christine, Rothblatt, Jonathan, Deleuze, Jean-Francois, Lin, Charles P., Karp, Jeffrey Michael
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: Elsevier 2016
Online Access:http://hdl.handle.net/1721.1/101703

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http://hdl.handle.net/1721.1/101703

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