Antisense transcription as a tool to tune gene expression

A surprise that has emerged from transcriptomics is the prevalence of genomic antisense transcription, which occurs counter to gene orientation. While frequent, the roles of antisense transcription in regulation are poorly understood. We built a synthetic system in Escherichia coli to study how anti...

Full description

Bibliographic Details
Main Authors: Brophy, Jennifer Ann, Voigt, Christopher A.
Other Authors: Massachusetts Institute of Technology. Synthetic Biology Center
Format: Article
Language:en_US
Published: Nature Publishing Group 2016
Online Access:http://hdl.handle.net/1721.1/101720
https://orcid.org/0000-0001-7808-4281
https://orcid.org/0000-0003-0844-4776