Neural innervation stimulates splenic TFF2 to arrest myeloid cell expansion and cancer

Neural innervation stimulates splenic TFF2 to arrest myeloid cell expansion and cancer

CD11b[superscript +]Gr-1[superscript +] myeloid-derived suppressor cells (MDSCs) expand in the spleen during cancer and promote progression through suppression of cytotoxic T cells. An anti-inflammatory reflex arc involving the vagus nerve and memory T cells is necessary for resolution of acute infl...

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Bibliographic Details
Main Authors: Dubeykovskaya, Zina, Si, Yiling, Chen, Xiaowei, Worthley, Daniel L., Renz, Bernhard W., Urbanska, Aleksandra M., Hayakawa, Yoku, Xu, Ting, Westphalen, C. Benedikt, Dubeykovskiy, Alexander, Chen, Duan, Friedman, Richard A., Asfaha, Samuel, Nagar, Karan, Tailor, Yagnesh, Muthupalani, Sureshkumar, Fox, James G., Kitajewski, Jan, Wang, Timothy C.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Nature Publishing Group 2016
Online Access:http://hdl.handle.net/1721.1/101724
https://orcid.org/0000-0001-9307-6116

Internet

http://hdl.handle.net/1721.1/101724
https://orcid.org/0000-0001-9307-6116

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