Genetically engineering self-organization of human pluripotent stem cells into a liver bud-like tissue using Gata6

Human induced pluripotent stem cells (hiPSCs) have potential for personalized and regenerative medicine. While most of the methods using these cells have focused on deriving homogenous populations of specialized cells, there has been modest success in producing hiPSC-derived organotypic tissues or o...

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Bibliographic Details
Main Authors: Guye, Patrick, Kipniss, Nathan, Velazquez, Jeremy J., Schoenfeld, Eldi, Kiani, Samira, Griffith, Linda G., Weiss, Ron, Ebrahimkhani, Mohammad Reza
Other Authors: MIT Synthetic Biology Center
Format: Article
Language:en_US
Published: Nature Publishing Group 2016
Online Access:http://hdl.handle.net/1721.1/101729
https://orcid.org/0000-0003-0396-2443
https://orcid.org/0000-0003-1736-0937
https://orcid.org/0000-0002-1801-5548