High-bandwidth AFM-based rheology is a sensitive indicator of early cartilage aggrecan degradation relevant to mouse models of osteoarthritis
Murine models of osteoarthritis (OA) and post-traumatic OA have been widely used to study the development and progression of these diseases using genetically engineered mouse strains along with surgical or biochemical interventions. However, due to the small size and thickness of murine cartilage, t...
Main Authors: | , , , , , , , |
---|---|
Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
Elsevier
2016
|
Online Access: | http://hdl.handle.net/1721.1/102071 https://orcid.org/0000-0003-3511-5679 https://orcid.org/0000-0003-1970-9901 https://orcid.org/0000-0002-4942-3456 |